Archive for category: Ferret

Interferon as an immunoadjuvant to enhance antibodies following influenza B infection and vaccination in ferrets

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Ampersand Biosciences was cited in the article titled, “Interferon as an immunoadjuvant to enhance antibodies following influenza B infection and vaccination in ferrets” for the use of a multiplex luminex assay kit containing ferret specific antibodies and proteins in a microsphere-based assay that consisted of antigen-specific antibodies covalently coupled to magnetic Luminex beads and biotinylated detection antibodies in a capture-sandwich format. This multiplex luminex assay was used to test levels of Type-I/II IFN (IFNB and IFNG), TH1/TH2 (IP-10 and IL-2), pro-inflammatory (MCP-1, MIP-1B, TNFA, IL-6, IL-8, and IL-23) and T-effector (IL-4, IL-17, IL-12p40, and IL-12p70) in ferret sera.

Species: Ferret
Focus: Influenza B

Delay of innate immune responses following influenza B virus infection affects the development of a robust antibody response in ferrets

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Ampersand Biosciences was cited in the article titled, “Delay of innate immune responses following influenza B virus infection affects the development of a robust antibody response in ferrets” for the use of a luminex ferret multiplex assay kit manufactured by Ampersand Biosciences.

Species: Ferret
Focus: Influenza B

Validation of Ferret Luminex Cytokine Assays with serum from ferrets infected with flu, stimulated whole blood and PBMCs

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Laurie Stephen of Ampersand Biosciences co-authored an article titled, “Validation of Ferret Luminex Cytokine Assays with serum from ferrets infected with flu, stimulated whole blood and PBMCs.” This article features biomarker development through immunologic analysis of respiratory infections in ferrets, expressed in HEK293 cells and purified for the following values: IL-1?, IL-2, IL-5, IL-6, IL-12 p40, IL-12p35, IL-17, IFN?, TNF?, & IP-10.

Species: Ferret
Focus: Human Respiratory Viruses, Influenza A (IAV), Severe Accurate Respiratory Syndrome (SARS), Respiratory Syncytial Virus

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