citations
Our product citations and images, offering your customers real-world validation from peer-reviewed scientific articles.
Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis.
Ampersand Biosciences was cited in the article titled, "Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis" for measuring cytokine and chemokine content in plasma samples that could measure drug exposure in mice of linagliptin, a DDP-4 (dipeptidyl peptidase-4) ihibitor.
December 24, 2024/by Geoff SanfordSpecies: Mouse
Focus: Sepsis induced pro-inflammatory cytokine and chemokine production.
Intracranial inoculation rapidly induces Nipah virus encephalitis in Syrian hamsters
Ampersand Biosciences was cited in the article titled, "Intracranial inoculation rapidly induces Nipah virus encephalitis in Syrian hamsters" for the use of Hamster Cytokine Panel 1 on brain samples to determine the presence of nine cytokines (IL-2, IL-4, IL-10, IL-6, IFN-?, MCP-1, MIP-1?, TNF-?, & VEGF) to study nipah virus encephalitis in hamsters.
October 27, 2024/by Geoff SanfordSpecies: Hamster
Focus: Nipah virus
Interferon as an immunoadjuvant to enhance antibodies following influenza B infection and vaccination in ferrets
Ampersand Biosciences was cited in the article titled, "Interferon as an immunoadjuvant to enhance antibodies following influenza B infection and vaccination in ferrets" for the use of a multiplex luminex assay kit containing ferret specific antibodies and proteins in a microsphere-based assay that consisted of antigen-specific antibodies covalently coupled to magnetic Luminex beads and biotinylated detection antibodies in a capture-sandwich format. This multiplex luminex assay was used to test levels of Type-I/II IFN (IFNB and IFNG), TH1/TH2 (IP-10 and IL-2), pro-inflammatory (MCP-1, MIP-1B, TNFA, IL-6, IL-8, and IL-23) and T-effector (IL-4, IL-17, IL-12p40, and IL-12p70) in ferret sera.
October 23, 2024/by Geoff SanfordSpecies: Ferret
Focus: Influenza B
Vaccine Platform Comparison: Protective Efficacy against Lethal Marburg Virus Challenge in the Hamster Model
Ampersand Biosciences was cited in the article titled, "Vaccine Platform Comparison: Protective Efficacy against Lethal Marburg Virus Challenge in the Hamster Model" for the use of the 9-plex hamster cytokine panel and its use in serum cytokine analysis on hamster serum samples. This cytokine panel was used to assess the values for IL-10, IL-2, IL-4, IL-6, IFN?, MCP-1, MIP-1?, TNF?, and VEGF.
August 4, 2024/by Geoff SanfordSpecies: Hamster
Focus: Marburg Virus
Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma
Ampersand Biosciences was cited in the article titled, "Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma" for the use of Rodent Map 4.0 on the Luminex platform to measure mouse plasma and cell supernatant cytokines. Analysis was performed on 42 analytes including: Analysis of 42 analytes; CCL6, CRP, Eotaxin, GCP-2, GMCSF, IFN?, IFN?, IL1?, IL1 beta, IL2, IL4, IL5, IL6, IL9, IL10, IL12p40, IL12p70, IL17A, IL18, IL23, IL27, IL28, Insulin, IP-10, KC/GRO, MCP-1, MCSF1, MDC, MIP-1?, MIP-1?, MIP-1?, MMP-9, NGAL, RAGE, PAI-1, SCF, TIMP-1, TNF?, TPO, TSLP, VCAM-1, VEGF-A.
May 31, 2024/by Geoff SanfordSpecies: Mouse
Focus: T-Cell Lymphoma
Pharmacodynamic changes in tumor and immune cells drive iberdomide’s clinical mechanisms of activity in relapsed and refractory multiple myeloma
Ampersand Biosciences was cited in the article titled, "Pharmacodynamic changes in tumor and immune cells drive iberdomide's clinical mechanisms of activity in relapsed and refractory multiple myeloma" for analyzing samples at their facility in Lake Clear, NY using Millipore kit HCD8MAG-17k 17-plex cytokine assay.
May 14, 2024/by Geoff SanfordSpecies: Human
Focus: Myeloma
Delay of innate immune responses following influenza B virus infection affects the development of a robust antibody response in ferrets
Ampersand Biosciences was cited in the article titled, "Delay of innate immune responses following influenza B virus infection affects the development of a robust antibody response in ferrets" for the use of a luminex ferret multiplex assay kit manufactured by Ampersand Biosciences.
February 18, 2024/by Geoff SanfordSpecies: Ferret
Focus: Influenza B
Viral codon optimization on SARS-CoV-2 Spike boosts immunity in the development of COVID-19 mRNA vaccines.
Ampersand Biosciences was cited in the article titled, "Viral codon optimization on SARS-CoV-2 Spike boosts immunity in the development of COVID-19 mRNA vaccines" for the measuring of secreted cytokines.
November 12, 2023/by Geoff SanfordSpecies: Mouse
Focus: Covid-19
Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation.
Ampersand Biosciences was cited in the article titled, "Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation" for the use of Roden Map 4.0 based on the Luminex platform.
September 10, 2023/by Geoff SanfordSpecies: Mouse
Focus: Huntington's Disease
The glucocorticoid receptor modulator relacorilant reverses the immunosuppressive effects of cortisol.
Ampersand Biosciences was cited in the article titled, "The glucocorticoid receptor modulator relacorilant reverses the immunosuppressive effects of cortisol" for managing experiments performed by Corcept Therpeutics to study glucocorticoid receptors.
June 15, 2023/by Geoff SanfordImpact of prior flavivirus vaccination on immunogenicity and efficacy of an inactivated Zika vaccine in Indian rhesus macaques.
Ampersand Biosciences was cited in the article titled, "Impact of prior flavivirus vaccination on immunogenicity and efficacy of an inactivated Zika vaccine in Indian rhesus macaques" for manufacturing a multiplex Luminex kit (Flavivirus Serological Panel) that included antigens from ZIKV, DENV, YFV, JEV, WNV, SLE, and Usutu virus that was used to select flavivirus naive macaques.
April 30, 2023/by Geoff SanfordSpecies: Human
Focus: Flavivirus, Zika Virus
Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation.
Ampersand Biosciences was cited in the article titled, "Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation" for the use of Mouse Map 4.1 luminex platform multiplex analysis.
April 12, 2023/by Geoff SanfordSpecies: Mouse
Focus: Lung mast cells
β-Arrestin-biased proteinase-activated receptor-2 antagonist C781 limits allergen-induced airway hyperresponsiveness and inflammation
Ampersand Biosciences was cited in the article titled, "β-Arrestin-biased proteinase-activated receptor-2 antagonist C781 limits allergen-induced airway hyperresponsiveness and inflammation" for the use of cyokine analysis using Mouse Map 4.1 multiplex immunoassay.
February 15, 2023/by Geoff SanfordSpecies: Mouse
Focus: Asthma
Head-to-head comparison of two SGLT-2 inhibitors on AKI outcomes in a rat ischemia-reperfusion model.
Ampersand Biosciences was cited in the article titled, "Head-to-head comparison of two SGLT-2 inhibitors on AKI outcomes in a rat ischemia-reperfusion model" for sample testing services that measured urinary kidney injury molecule-1 (KIM-1) using a sandwich enzyme immunoassay.
September 7, 2022/by Geoff SanfordSpecies: Rat
Focus: Acute Kidney Injury (AKI)
Validation of Ferret Luminex Cytokine Assays with serum from ferrets infected with flu, stimulated whole blood and PBMCs
Laurie Stephen of Ampersand Biosciences co-authored an article titled, "Validation of Ferret Luminex Cytokine Assays with serum from ferrets infected with flu, stimulated whole blood and PBMCs." This article features biomarker development through immunologic analysis of respiratory infections in ferrets, expressed in HEK293 cells and purified for the following values: IL-1?, IL-2, IL-5, IL-6, IL-12 p40, IL-12p35, IL-17, IFN?, TNF?, & IP-10.
May 1, 2022/by Geoff SanfordSpecies: Ferret
Focus: Human Respiratory Viruses, Influenza A (IAV), Severe Accurate Respiratory Syndrome (SARS), Respiratory Syncytial Virus
Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis.
Ampersand Biosciences was cited in the article titled, "Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis" for performing analysis of a panel of cytokines/chemokines on liver homogenates.
April 24, 2022/by Geoff SanfordSpecies: Human, Mouse
Focus: Hepatic diseases, Liver Fibrosis
e-Cigarette Aerosol Reduces Left Ventricular Function in Adolescent Mice.
Ampersand Biosciences was cited in the article titled, "e-Cigarette Aerosol Reduces Left Ventricular Function in Adolescent Mice" for analysis of biomarkers using immunoassay in adolescent male mice.
April 17, 2022/by Geoff SanfordSpecies: Mouse
Focus: Vaping, Electronic Cigarettes, Adolescent Cardiac Health
A high throughput reporter virus particle microneutralization assay for quantitation of Zika virus neutralizing antibodies in multiple species.
Ampersand Biosciences was cited in the article titled, "A high throughput reporter virus particle microneutralization assay for quantitation of Zika virus neutralizing antibodies in multiple species" for luminex assay on flavivirus-binding antibodies.
September 28, 2021/by Geoff SanfordSpecies: Rabbit, Human
Focus: Flavivirus, Zika Virus
A clinically relevant murine model unmasks a “two-hit” mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant.
Ampersand Biosciences was cited in the article titled, "A clinically relevant murine model unmasks a “two-hit” mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant" for analyzing inflammatory proteins using the Luminex System and the Roden Map 4.0 multiplex assay.
September 22, 2020/by Geoff SanfordSpecies: Mouse
Focus: Cytomegalovirus, Kidney Transplant
Complete Protection in Macaques Conferred by Purified Inactivated Zika Vaccine: Defining a Correlate of Protection
Ampersand Biosciences was cited in the article titled, "Complete Protection in Macaques Conferred by Purified Inactivated Zika Vaccine: Defining a Correlate of Protection" for use of a multiplex Luminex Kit (Flavivirus Serological Panel) to determine baseline igG serostatus.
February 25, 2020/by Geoff SanfordSpecies: Human
Focus: Zika Virus, Zika Vaccine (PIZV)
Short-Term Pulmonary Toxicity Assessment of Pre- and Post-incinerated Organomodified Nanoclay in Mice.
Ampersand Biosciences was cited in the article titled, "Short-Term Pulmonary Toxicity Assessment of Pre- and Post-incinerated Organomodified Nanoclay in Mice" for use of sample testing services featuring a 17 target cytokine magnetic Luminex bead array that was designed to assay all collected BAL samples from a large animal study. All bead and ELISA assays were conducted on neat samples.
August 4, 2019/by Geoff SanfordSpecies: Mouse
Focus: Organomodified nanoclays (ONCS), Pulmonary Toxicity, Long-term Occupational Exposures, Pulmonary Health
Nintedanib reduces pulmonary fibrosis in a model of rheumatoid arthritis-associated interstitial lung disease
Ampersand Biosciences was cited in the article titled, "Nintedanib reduces pulmonary fibrosis in a model of rheumatoid arthritis-associated interstitial lung disease" for analysis of 42 molecules by multiplex ELISA Rodent Map 4.0 at Ampersand Biosciences in Saranac Lake.
May 31, 2019/by Geoff SanfordSpecies: Mouse
Focus: Rheumatoid Arthritis (RA), Interstitial lunge disease (RA-ILD)
Therapeutic efficacy of anti-MMP9 antibody in combination with nab-paclitaxel-based chemotherapy in pre-clinical models of pancreatic cancer
Ampersand Biosciences was cited in the article titled, "Therapeutic efficacy of anti-MMP9 antibody in combination with nab-paclitaxel-based chemotherapy in pre-clinical models of pancreatic cancer" for the Luminex analysis of samples tested performed with Rodent Map 4.0 Mouse panel at Ampersand Biosciences in Saranac Lake, NY.
April 1, 2019/by Geoff SanfordSpecies: Mouse
Focus: Matrix metalloproteinase 9 (MMP9), Pancreatic Ductal Adenocarcinoma (PDAC), aMMP9
MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors
Ampersand Biosciences was cited in the article titled, "MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors" for sample testing services performed at Ampersand Biosciences in Saranac Lake, NY. Lysates were analyzed via Luminex analysis using the Rodent Map 4.0 mouse panel.
November 29, 2018/by Geoff SanfordSpecies: Mouse
Focus: Matrix metalloproteinase 9 (MMP9), Cancer, Tracking of effector/memory T-Cells into tumors, Intratumoral T-Cell diversity
Multiplex Immunoassay Profiling of Hormones Involved in Metabolic Regulation
Laurie Stephen of Ampersand Biosciences co-authored a protocol titled, "Multiplex Immunoassay Profiling of Hormones Involved in Metabolic Regulation." This article features multiplex immunassays used for rapid profiling of biomarker proteins and small molecules in biological fluids.
January 28, 2018/by Geoff SanfordNecroptotic debris including damaged mitochondria elicits sepsis-like syndrome during late-phase tularemia
Laurie Stephen of Ampersand Biosciences co-authored an article titled, "Necroptotic debris including damaged mitochondria elicits sepsis-like syndrome during late-phase tularemia."
June 30, 2017/by Geoff SanfordSpecies: Mouse, Non-Human Primates, Humans
Focus: Francisella Tularensis Ssp. Tularensis (Ft), SchuS4, Tularemia
Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen
Ampersand Biosciences was cited in the article titled, "Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen" for the use of sample testing services performed by Ampersand Biosciences using the Roden Map 4.0 cytokine bead array to measure cytokine and protein levels.
April 5, 2017/by Geoff SanfordSpecies: Mouse
Focus: Immune Response, Gene Expression, Ummostimulatory Ligands, Lipopolysaccharide
Multiplex Immunoassay Profiling of Serum in Psychiatric Disorders
Laurie Stephen of Ampersand Biosciences co-authored a chapter in Proteomic Methods in Neuropsychiatric Research titled, "Multiplex Immunoassay Profiling of Serum in Psychiatric Disorders." This chapter features multiplex immunoassays that allow for rapid profiling of biomarker proteins in biological fluids, using less sample and labor than in single immunoassays.
March 29, 2017/by Geoff SanfordComprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells.
Ampersand Biosicences was cited in the article titled, "Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells" for sample testing analysis performed by Ampersand Biosciences using 42 biomarkers on the Rodent Map v.4.0 platform.
December 21, 2016/by Geoff SanfordSpecies: Mouse
Focus: Extracellular Vesicles (EVs)
Recommendations for Use and Fit-for-Purpose Validation of Biomarker Multiplex Ligand Binding Assays in Drug Development
Laurie Stephen of Ampersand Biosciences co-authored an article in the AAPS Journal titled, "Recommendations for Use and Fit-for-Purpose Validation of Biomarker Multiplex Ligand Binding Assays in Drug Development." This article features multiplex assays and their complexity, how they create many unique challenges, and the purpose of biomarker multiplex ligand binding assays in drug development.
December 31, 2015/by Geoff SanfordValidation of a Multivariate Serum Profile for Epithelial Ovarian Cancer Using a Prospective Multi-Site Collection
Laurie Stephen of Ampersand Biosciences co-authored an article in Nature Precedings titled, "Validation of a Multivariate Serum Profile for Epithelial Ovarian Cancer Using a Prospective Multi-Site Collection." This article describes the use of retrospective collection of ovarian cancer and benign disease samples, in combination with a large set of multiplex immunoassays.
July 20, 2010/by Geoff Sanford