Pharmacodynamic changes in tumor and immune cells drive iberdomide's clinical mechanisms of activity in relapsed and refractory multiple myeloma
Ampersand Biosciences was cited in the article titled, “Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis” for measuring cytokine and chemokine content in plasma samples that could measure drug exposure in mice of linagliptin, a DDP-4 (dipeptidyl peptidase-4) ihibitor.
Species: Mouse
Focus: Sepsis induced pro-inflammatory cytokine and chemokine production.