Archive for category: Mouse

Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis.

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Ampersand Biosciences was cited in the article titled, “Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis” for measuring cytokine and chemokine content in plasma samples that could measure drug exposure in mice of linagliptin, a DDP-4 (dipeptidyl peptidase-4) ihibitor.

Species: Mouse
Focus: Sepsis induced pro-inflammatory cytokine and chemokine production.

Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma

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Ampersand Biosciences was cited in the article titled, “Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma” for the use of Rodent Map 4.0 on the Luminex platform to measure mouse plasma and cell supernatant cytokines. Analysis was performed on 42 analytes including: Analysis of 42 analytes; CCL6, CRP, Eotaxin, GCP-2, GMCSF, IFN?, IFN?, IL1?, IL1 beta, IL2, IL4, IL5, IL6, IL9, IL10, IL12p40, IL12p70, IL17A, IL18, IL23, IL27, IL28, Insulin, IP-10, KC/GRO, MCP-1, MCSF1, MDC, MIP-1?, MIP-1?, MIP-1?, MMP-9, NGAL, RAGE, PAI-1, SCF, TIMP-1, TNF?, TPO, TSLP, VCAM-1, VEGF-A.

Species: Mouse
Focus: T-Cell Lymphoma

Viral codon optimization on SARS-CoV-2 Spike boosts immunity in the development of COVID-19 mRNA vaccines.

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Ampersand Biosciences was cited in the article titled, “Viral codon optimization on SARS-CoV-2 Spike boosts immunity in the development of COVID-19 mRNA vaccines” for the measuring of secreted cytokines.

Species: Mouse
Focus: Covid-19

Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation.

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Ampersand Biosciences was cited in the article titled, “Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation” for the use of Roden Map 4.0 based on the Luminex platform.

Species: Mouse
Focus: Huntington’s Disease

Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation.

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Ampersand Biosciences was cited in the article titled, “Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation” for the use of Mouse Map 4.1 luminex platform multiplex analysis.

Species: Mouse
Focus: Lung mast cells

β-Arrestin-biased proteinase-activated receptor-2 antagonist C781 limits allergen-induced airway hyperresponsiveness and inflammation

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Ampersand Biosciences was cited in the article titled, “β-Arrestin-biased proteinase-activated receptor-2 antagonist C781 limits allergen-induced airway hyperresponsiveness and inflammation” for the use of cyokine analysis using Mouse Map 4.1 multiplex immunoassay.

Species: Mouse
Focus: Asthma

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