Human SPARC Monoclonal Antibody (SPC-5H7-2C3)
Secreted protein acidic and rich in cysteine (SPARC), aka osteonectin, UniProt # P09486, is a glycoprotein secreted by a variety of cells and tumors. The biological functions of SPARC vary and include tissue remodeling as well as apoptosis. SPARC is considered a tumor inhibitor in various cancers such as breast, colorectal, pancreatic, and ovarian.