Archive for category: Citations

Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis.

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Ampersand Biosciences was cited in the article titled, “Dipeptidyl peptidase-4 inhibitor linagliptin reduces inflammatory response, ameliorates tissue edema formation, and improves survival in severe sepsis” for measuring cytokine and chemokine content in plasma samples that could measure drug exposure in mice of linagliptin, a DDP-4 (dipeptidyl peptidase-4) ihibitor.

Species: Mouse
Focus: Sepsis induced pro-inflammatory cytokine and chemokine production.

Intracranial inoculation rapidly induces Nipah virus encephalitis in Syrian hamsters

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Ampersand Biosciences was cited in the article titled, “Intracranial inoculation rapidly induces Nipah virus encephalitis in Syrian hamsters” for the use of Hamster Cytokine Panel 1 on brain samples to determine the presence of nine cytokines (IL-2, IL-4, IL-10, IL-6, IFN-?, MCP-1, MIP-1?, TNF-?, & VEGF) to study nipah virus encephalitis in hamsters.

Species: Hamster
Focus: Nipah virus

Interferon as an immunoadjuvant to enhance antibodies following influenza B infection and vaccination in ferrets

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Ampersand Biosciences was cited in the article titled, “Interferon as an immunoadjuvant to enhance antibodies following influenza B infection and vaccination in ferrets” for the use of a multiplex luminex assay kit containing ferret specific antibodies and proteins in a microsphere-based assay that consisted of antigen-specific antibodies covalently coupled to magnetic Luminex beads and biotinylated detection antibodies in a capture-sandwich format. This multiplex luminex assay was used to test levels of Type-I/II IFN (IFNB and IFNG), TH1/TH2 (IP-10 and IL-2), pro-inflammatory (MCP-1, MIP-1B, TNFA, IL-6, IL-8, and IL-23) and T-effector (IL-4, IL-17, IL-12p40, and IL-12p70) in ferret sera.

Species: Ferret
Focus: Influenza B

Vaccine Platform Comparison: Protective Efficacy against Lethal Marburg Virus Challenge in the Hamster Model

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Ampersand Biosciences was cited in the article titled, “Vaccine Platform Comparison: Protective Efficacy against Lethal Marburg Virus Challenge in the Hamster Model” for the use of the 9-plex hamster cytokine panel and its use in serum cytokine analysis on hamster serum samples. This cytokine panel was used to assess the values for IL-10, IL-2, IL-4, IL-6, IFN?, MCP-1, MIP-1?, TNF?, and VEGF.

Species: Hamster
Focus: Marburg Virus

Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma

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Ampersand Biosciences was cited in the article titled, “Epigenetic Priming by Hypomethylation Enhances the Immunogenic Potential of Tolinapant in T-cell Lymphoma” for the use of Rodent Map 4.0 on the Luminex platform to measure mouse plasma and cell supernatant cytokines. Analysis was performed on 42 analytes including: Analysis of 42 analytes; CCL6, CRP, Eotaxin, GCP-2, GMCSF, IFN?, IFN?, IL1?, IL1 beta, IL2, IL4, IL5, IL6, IL9, IL10, IL12p40, IL12p70, IL17A, IL18, IL23, IL27, IL28, Insulin, IP-10, KC/GRO, MCP-1, MCSF1, MDC, MIP-1?, MIP-1?, MIP-1?, MMP-9, NGAL, RAGE, PAI-1, SCF, TIMP-1, TNF?, TPO, TSLP, VCAM-1, VEGF-A.

Species: Mouse
Focus: T-Cell Lymphoma

Pharmacodynamic changes in tumor and immune cells drive iberdomide's clinical mechanisms of activity in relapsed and refractory multiple myeloma

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Ampersand Biosciences was cited in the article titled, “Pharmacodynamic changes in tumor and immune cells drive iberdomide’s clinical mechanisms of activity in relapsed and refractory multiple myeloma” for analyzing samples at their facility in Lake Clear, NY using Millipore kit HCD8MAG-17k 17-plex cytokine assay.

Species: Human
Focus: Myeloma

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