A clinically relevant murine model unmasks a "two-hit" mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant.

Ampersand Biosciences was cited in the article titled, “A clinically relevant murine model unmasks a “two-hit” mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant” for analyzing inflammatory proteins using the Luminex System and the Roden Map 4.0 multiplex assay.

Species: Mouse
Focus: Cytomegalovirus, Kidney Transplant

Complete Protection in Macaques Conferred by Purified Inactivated Zika Vaccine: Defining a Correlate of Protection

Ampersand Biosciences was cited in the article titled, “Complete Protection in Macaques Conferred by Purified Inactivated Zika Vaccine: Defining a Correlate of Protection” for use of a multiplex Luminex Kit (Flavivirus Serological Panel) to determine baseline igG serostatus.

Species: Human
Focus: Zika Virus, Zika Vaccine (PIZV)

Short-Term Pulmonary Toxicity Assessment of Pre- and Post-incinerated Organomodified Nanoclay in Mice.

Ampersand Biosciences was cited in the article titled, “Short-Term Pulmonary Toxicity Assessment of Pre- and Post-incinerated Organomodified Nanoclay in Mice” for use of sample testing services featuring a 17 target cytokine magnetic Luminex bead array that was designed to assay all collected BAL samples from a large animal study. All bead and ELISA assays were conducted on neat samples.

Species: Mouse
Focus: Organomodified nanoclays (ONCS), Pulmonary Toxicity, Long-term Occupational Exposures, Pulmonary Health

Nintedanib reduces pulmonary fibrosis in a model of rheumatoid arthritis-associated interstitial lung disease

Ampersand Biosciences was cited in the article titled, “Nintedanib reduces pulmonary fibrosis in a model of rheumatoid arthritis-associated interstitial lung disease” for analysis of 42 molecules by multiplex ELISA Rodent Map 4.0 at Ampersand Biosciences in Saranac Lake.

Species: Mouse
Focus: Rheumatoid Arthritis (RA), Interstitial lunge disease (RA-ILD)

Therapeutic efficacy of anti-MMP9 antibody in combination with nab-paclitaxel-based chemotherapy in pre-clinical models of pancreatic cancer

Ampersand Biosciences was cited in the article titled, “Therapeutic efficacy of anti-MMP9 antibody in combination with nab-paclitaxel-based chemotherapy in pre-clinical models of pancreatic cancer” for the Luminex analysis of samples tested performed with Rodent Map 4.0 Mouse panel at Ampersand Biosciences in Saranac Lake, NY.

Species: Mouse
Focus: Matrix metalloproteinase 9 (MMP9), Pancreatic Ductal Adenocarcinoma (PDAC), aMMP9

MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors

Ampersand Biosciences was cited in the article titled, “MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors” for sample testing services performed at Ampersand Biosciences in Saranac Lake, NY. Lysates were analyzed via Luminex analysis using the Rodent Map 4.0 mouse panel.

Species: Mouse
Focus: Matrix metalloproteinase 9 (MMP9), Cancer, Tracking of effector/memory T-Cells into tumors, Intratumoral T-Cell diversity